Phenomenological Load on Model Parameters Can Lead to False Biological Conclusions

Using the wrong model can lead to unsupported conclusions about glucose meters.

Van Herpe et al. (1 ) modeled the effect of glucose sensor errors to provide total error acceptability limits to prevent harm to patients. In particular, the authors state that if the total error is 15.7%, the probability is zero that glucose meter results will fall in the D zone (causes severe injury or death) of a glucose meter error grid. This cannot be true for several reasons. The authors ...

Neural evidence that vivid imagining can lead to false remembering.

The imperfect nature of memory is highlighted by the regularity with which people fail to remember, or worse, remember something that never happened. We investigated the formation of a particular type of erroneous memory by monitoring brain activity using functional magnetic resonance imaging during the presentation of words and photos. Participants generated a visual image of a common object i...

Cox Model Setup May Lead to Erroneous Conclusions

Pnm-12: Can Stress Lead to Infertility?

Background: The role that stress plays in infertility remains controversial and despite medical advances a large percentage of infertility remains unexplained. Clinicians and researchers consistently report that infertile women view infertility and its treatment as extremely stressful. Basic science has elucidated the linkages between the hypothalamic-pituitary axis (HPA) and hypothalamic-pitui...

Too much statistical power can lead to false conclusions: a response to 'Unsuitability of the epidemiological approach to bicycle transportation injuries and traffic engineering problems' by Kary.

Injury Prevention recently published a commentary critical of epidemiological approaches to cycling safety. The author, Kary, suggests that our paper, which reanalysed Walker’s study of motor vehicle overtaking distance for cyclists, made false claims about type I errors and confused statistical significance and clinical significance. Kary supports this critique, along with other points in the ...